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KMID : 0381219900220020210
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Journal of RIMSK
1990 Volume.22 No. 2 p.210 ~ p.214
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A Case of Anesthetic Management of Diabetes Insipidus Complicated by Craniopharyngioma
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Abstract
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Diabetes insipidus (DI) is a clinical syndrome that results from inadequate production of, or inadequate response to arginine vasopressin (AVP). The causes of DI are vasopressin deficiency (neurogenic DI), excessive water intake (primary polydipsia) and vasopressin insensitivity (nephrogenic DI). The clinical manifestations of DI are polyuria and polydipsia. The tonicity of urine is usually hypotonic compared with that of plasma. The urine osmolarity is usually less than 200 mOsm/ L, and urine specific gravity is less than 1.005. The goal of perioperative management of DI is to maintain fluid and electrolyte balance, normal urine output and hemodynamic stability. We experienced a case of anesthetic management of DI complicated by craniopharyngioma. The clinical symptoms of DI disappeared after tumor removal, and urine osmolarity and urine specific gravity were subsequently normalized.
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